If you have priced a GLP-1 program online lately, you have probably noticed that the number in the ad and the number on your card statement are two different things. A membership appears at checkout. The pen costs more once your provider moves you up a dose. A friendly first-month price quietly renews at nearly double. None of that is hidden, exactly, but it is scattered across fine print, FAQ pages and terms of service.

So we sat down with six well-known telehealth programs and read every pricing page, plan page and set of terms we could find, the way you would if you had a free afternoon and a spreadsheet. This guide is the result: what each one costs for tirzepatide and for semaglutide, what you pay on top, what changes over time, and which one we would point a friend to.

The short answer

For most people paying out of pocket, Biotech Lifestyle is the one we recommend

  1. Nothing billed on top of the medication There is no membership, program or enrollment fee. The provider visit, normally $49.99, is waived, and shipping is included. Compare that with Hims & Hers, Ro and LifeMD, which each charge $149 every month before you buy a single dose.
  2. On the 90-day plan your price stays put as your dose changes Most people step up their dose a few times early on. On Biotech Lifestyle's 90-day plans every vial strength costs the same, while brand-name Zepbound and Wegovy get pricier at each step.
  3. An easy start with no year-long commitment The first month is $79 for semaglutide or $99 for tirzepatide. After that the 90-day plans run $240 or $330 for 90 days at every dose, and you can change or cancel whenever you need to.
  4. It arrives ready to use Vitamin B12 is part of the formulation, syringes and swabs come in the box, it ships UPS Next Day Air, and you can message your provider as treatment goes on. HSA and FSA cards work.

A licensed provider evaluates you before anything is prescribed. Compounded medications are made by licensed pharmacies for individual patients and are not FDA-approved.

What Six Online GLP-1 Programs Really Charge for Tirzepatide and Semaglutide

What we looked at, and how

We only used what each company publishes itself, read on October 1, 2026. No promo codes, no affiliate pricing, no roundup sites. When a provider does not publish a number, we say that instead of filling in a guess. Prices move, so double check on the provider's own site before you pay.

Semaglutide prices, side by side

Semaglutide is the medication in Wegovy and Ozempic. Hims & Hers, Ro and LifeMD sell the brand-name Wegovy pen and add their membership. Biotech Lifestyle, Noom Med and Shed prescribe compounded semaglutide, and the medication is part of the price you see.

Semaglutide
Our pickBiotech LifestyleVisit Biotech Lifestyle
ComparedHims & HersVisit Hims & Hers
ComparedRoVisit Ro
ComparedLifeMDVisit LifeMD
ComparedNoom MedVisit Noom Med
ComparedShedVisit Shed
Price
  • $79 first month, then $103 to $128 per month by dose
  • $240 per 90 days on the 90-day plan, which is $80 per month at every dose
  • 90-day price never changes with dose
  • From $199 per month for brand-name Wegovy pen (medication only); Wegovy pill from $149
  • Plus the membership below. Lowest-dose total: $348 per month
  • From $199 per month for brand-name Wegovy pen (medication only); Wegovy pill $149
  • Plus the membership below. Lowest-dose total: $348 per month on the monthly plan
  • From $199 per month for brand-name Wegovy pen (medication only)
  • Plus the program fee below. Lowest-dose total: $348 per month
  • $129 for the first 4 weeks
  • then $249 per month, billed every 12 weeks ($747 per quarter)
  • $199 per month, month to month
  • $179 per month on a 6-month plan
  • $159 per month on a 12-month plan
Membership fees$0. No membership, program or enrollment fee. The provider visit is included, a $49.99 value that is waived.$149 per month membership $39 for the first month, then $149 every month, billed separately from the medication and required to stay on treatment.$149 per month membership $39 for the first month, then $149 per month. Drops to $99, $89 or $74 per month only if you prepay 3, 6 or 12 months. Medication is billed on top.$149 per month membership $39 for the first month, then $149 a month for the program. Medication cost is not included. Program fees are not refunded if your insurance will not cover the medication.$0 separate fee. Clinical care, medication and the Noom app are bundled into one price (GLP-1Rx program).Bundled. The terms describe a membership fee that is non-refundable once you are approved; no separate amount is published.
Price increasesNone on the 90-day plan. One price at every vial strength there; monthly is priced by dose. No membership to renew. Adjust or cancel anytime.Yes. Brand-name Wegovy is priced by dose, so the medication line rises as your dose goes up. The $149 membership renews on top every month.Yes. Brand-name Wegovy is priced by dose. The membership renews every month, or every 3, 6 or 12 months if prepaid.Yes. Brand-name Wegovy is priced by dose. The $149 program fee renews monthly.Yes. From $129 to $249 after the first month.No. Flat across doses. Multi-month plans carry a minimum term with no refund inside it.
FeaturesCompounded semaglutide with vitamin B12. Licensed provider evaluation, syringes and swabs, UPS Next Day Air shipping, ongoing provider messaging and dose adjustments. HSA and FSA accepted.Brand-name Wegovy (FDA-approved), not compounded. Provider evaluation, ongoing care through the membership, app messaging.Brand-name Wegovy (FDA-approved), not compounded. Provider support, side-effect management and dose adjustments through the Ro Body membership. Insurance checker for brand coverage.Brand-name Wegovy (FDA-approved), not compounded. Clinician consultations, coaching, lab work, insurance assistance. Medicare and other government coverage not eligible.Compounded semaglutide. Clinician evaluation, the Noom app with daily lessons and coaching, food and weight tracking. HSA and FSA eligible. Not available in all states.Compounded semaglutide. Unlimited provider visits, free standard shipping, tracking app, text-based coaching, nurse and nutritionist access. HSA and FSA eligible.

On a phone, swipe the table left to see every program. The $348 figure is the $149 membership added to the lowest-dose Wegovy pen. After its first month, Noom Med bills in twelve-week blocks, and Shed's lowest rate comes with a twelve-month plan.

Tirzepatide prices, side by side

Tirzepatide works on two hormone pathways, GIP and GLP-1, and is the medication in Zepbound and Mounjaro. The split is the same as above: brand-name pens and vials plus a membership at three programs, compounded tirzepatide at an all-in price at the other three.

Tirzepatide
Our pickBiotech LifestyleVisit Biotech Lifestyle
ComparedHims & HersVisit Hims & Hers
ComparedRoVisit Ro
ComparedLifeMDVisit LifeMD
ComparedNoom MedVisit Noom Med
ComparedShedVisit Shed
Price
  • $99 first month, then $128 to $184 per month by dose
  • $330 per 90 days on the 90-day plan, which is $110 per month at every dose
  • 90-day price never changes with dose
  • From $299 per month for brand-name Zepbound (medication only)
  • Plus the membership below. Lowest-dose total: $448 per month
  • From $299 per month for brand-name Zepbound KwikPen (medication only)
  • Plus the membership below. Lowest-dose total: $448 per month on the monthly plan
  • From $299 per month for brand-name Zepbound vial (medication only)
  • Plus the program fee below. Lowest-dose total: $448 per month
  • $149 for the first 4 weeks
  • then $299 per month, billed every 12 weeks ($897 per quarter)
  • $299 per month, month to month
  • $269 per month on a 6-month plan
  • $239 per month on a 12-month plan
Membership fees$0. No membership, program or enrollment fee. The provider visit is included, a $49.99 value that is waived.$149 per month membership $39 for the first month, then $149 every month, billed separately from the medication and required to stay on treatment.$149 per month membership $39 for the first month, then $149 per month. Drops to $99, $89 or $74 per month only if you prepay 3, 6 or 12 months. Medication is billed on top.$149 per month membership $39 for the first month, then $149 a month for the program. Medication cost is not included. Program fees are not refunded if your insurance will not cover the medication.$0 separate fee. Clinical care, medication and the Noom app are bundled into one price (GLP-1Rx Plus program).Bundled. The terms describe a membership fee that is non-refundable once you are approved; no separate amount is published.
Price increasesNone on the 90-day plan. One price at every vial strength there; monthly is priced by dose. No membership to renew. Adjust or cancel anytime.Yes. Brand-name Zepbound is priced by dose, so the medication line rises as your dose goes up. The $149 membership renews on top every month.Yes. Brand-name Zepbound is priced by dose. The membership renews every month, or every 3, 6 or 12 months if prepaid.Yes. Brand-name Zepbound is priced by dose. The $149 program fee renews monthly.Yes. The price doubles after the first month, from $149 to $299.No. Flat across doses. Multi-month plans carry a minimum term with no refund inside it.
FeaturesCompounded tirzepatide with vitamin B12. Licensed provider evaluation, syringes and swabs, UPS Next Day Air shipping, ongoing provider messaging and dose adjustments. HSA and FSA accepted.Brand-name Zepbound (FDA-approved), not compounded. Provider evaluation, ongoing care through the membership, app messaging. Zepbound also offered at $1,899 per month as a single-dose pen.Brand-name Zepbound (FDA-approved), not compounded. Provider support, side-effect management and dose adjustments through the Ro Body membership. Insurance checker for brand coverage.Brand-name Zepbound (FDA-approved), not compounded. Clinician consultations, coaching, lab work, insurance assistance. Medicare and other government coverage not eligible.Compounded tirzepatide. Clinician evaluation, the Noom app with daily lessons and coaching, food and weight tracking. HSA and FSA eligible. Not available in all states.Compounded tirzepatide. Unlimited provider visits, free standard shipping, tracking app, text-based coaching, nurse and nutritionist access. HSA and FSA eligible.

The Zepbound "from" price is set by the manufacturer for the lowest dose only. The $448 figure adds the $149 membership to it. Biotech Lifestyle's prices are the ones listed on biotechlifestyle.com today, and its quarterly plan is a single payment that covers 90 days.

What Six Online GLP-1 Programs Really Charge for Tirzepatide and Semaglutide

When another program could be the better fit

We would not send everyone to the same place. If your insurance covers brand-name Zepbound or Wegovy and that is what you want, the membership programs are built for you, and LifeMD will even run the coverage check. Just know what the fee adds up to if you end up paying cash: after the $39 first month, it is $149 a month, or $1,639 over the next eleven months, with medication still to come. If daily lessons and coaching are what keep you on track, Noom Med has the most developed app here, as long as the jump after the first four weeks fits your budget. Shed comes closest on price and also charges the same at every dose, though its best rate asks for a twelve-month plan. If none of those describes you, a single flat price with no fees and no lock-in is the easiest plan to budget for, which is why Biotech Lifestyle comes out on top.

What other customers say

Star ratings will not tell you everything, but they are good at surfacing the things people complain about after the sale: surprise charges, late deliveries, a hard time canceling. Below is each program's current Trustpilot score, pulled straight from Trustpilot, and a public Google rating where we could find one (checked October 1, 2026). Click any score to read the reviews behind it.

Trustpilot scores refresh automatically and are shown here without review counts. Skim the most recent reviews yourself before deciding.

Five questions to ask any program

Put these to any GLP-1 program before you hand over a card number. For the six above, the answers are already in the tables.

A note on brand-name versus compounded

Zepbound and Wegovy are FDA-approved brand-name products, and their makers set a price for each dose. Biotech Lifestyle, Noom Med and Shed prescribe compounded versions instead, made by licensed pharmacies for each individual patient; compounded medications are not FDA-approved. All six programs require a licensed provider to evaluate you before prescribing, and no program can guarantee how much weight you will lose. Your coverage, your budget and your provider's advice should drive the decision. This guide is here to make the cost part of it easier to see.